OREXIN-1-RECEPTOR BLOCKER, SB-334867 MAY AFFECT BODY WEIGHT AND PROTECT AGAINST HYPOGLYCEMIA INDUCED BY PARADOXICAL SLEEP DEPRIVATION IN ADULT MALE RATS
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چکیده
منابع مشابه
Caffeine attenuates paradoxical sleep deprivation induced- memory impairment during paradoxical sleep windows in rats
There is considerable evidence to support the hypothesis of relationship between paradoxical sleep (PS) and learning–memory processing. It has been suggested that PS is important in memory retention at the specific time course called PS windows (PSW). The time of PSWs occurrence and duration of these PSWs following the training sessions and, the neurochemical nature of PSWs has not been well kn...
متن کاملCaffeine attenuates paradoxical sleep deprivation induced- memory impairment during paradoxical sleep windows in rats
There is considerable evidence to support the hypothesis of relationship between paradoxical sleep (PS) and learning–memory processing. It has been suggested that PS is important in memory retention at the specific time course called PS windows (PSW). The time of PSWs occurrence and duration of these PSWs following the training sessions and, the neurochemical nature of PSWs has not been well kn...
متن کاملAdministration of orexin receptor 1 antagonist into the rostral ventromedial medulla increased swim stress-induced antinociception in rat
Objective(s): Intracerebroventricular injection of orexin-A (hypocretin-1) antagonist has been shown to inhibit stress-induced analgesia. However the locations of central sites that may mediate these effects have not been totally demonstrated. This study was performed to investigate the role of rostral ventromedial medulla (RVM) orexin receptor 1 in stress-induced analgesia (SIA). Materials and...
متن کاملAngiotensin Type-1 Receptor Blockade May Not Protect Kidney against Cisplatin-Induced Nephrotoxicity in Rats
Background. Cisplatin (CDDP) is an anticancer drug, which is accompanied with major side effects including nephrotoxicity. We tested two doses of losartan (10 and 20 mg/kg/day) against nephrotoxicity in a rat model treated with daily administration of CDDP (2.5 mg/kg/day). Methods. Five groups of rats were examined. Groups 1 and 2 received losartan 10 and 20 mg/kg/day, i.p, for a period of 10 d...
متن کاملAssesment of orexin receptor 1 in stress attenuated nociceptive behaviours in formalin test
Introduction: It is known that acute and chronic stress induce hormonal and neuronal changes which affecting both pain threshold and nociceptive behaviours. Orexin plays an important role in modulation of pain and stress. Considering pain modulation during stress and the role of orexin in pain and stress, orexin might be involved in pain modulation during stress.We evaluated the involvement ...
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ژورنال
عنوان ژورنال: Bulletin of Egyptian Society for Physiological Sciences
سال: 2019
ISSN: 2356-9514
DOI: 10.21608/besps.2019.6809.1013